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A complete book for screening of drugs both in vivo and in vitro models for drugs of all classes viz. autonomic nervous system, central nervous system, analgesics, anti-inflammatory, cardiovascular and neurological disorders, cancer, HIV, diabetes, stem cells, antiemetics, absorption and metabolism, hormones, ophthalmic diseases, etc. the chapter on Newer Tools for Drug Screening has been updated providing information on novel concepts like cassette dosing, virtual screening application of LC-MS/MS in bioanalysis, etc. The readers should find the chapter on Stem Cell Therapy, interesting and informative to read. Comprehensive chapters on Cell-based Assays in High-throughput Screening of Drugs and Screening of Antiviral Agents have been new editions in this edition. Chapters on difficult and challenging areas of research like Diabetic Retinopathy, Ocular Inflammation and Ocular Toxicity have been complied, and it is hoped that it would open up renewed interest for research on these topics. All the chapters are well- elucidated and have been authored by the researchers with a vast experience and actively worki8ng in the area in India and abroad.