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This book “Novel Insights on SGLT-2 Inhibitors” is an effort on our part to present to the readers an insight into how these agents came into being and have fast evolved today as potent antidiabetic drugs occupying the coveted place of preferred agents in all diabetes management algorithms globally owing to their efficacy, durability as well as pleiotropic benefits and cardiorenal protective effects. This book is a humble effort on our part to update the busy internists and primary physicians who because of their busy practices cannot find enough time to update themselves with the current concepts and placement as well as the future prospects of these new drugs in the management of diabetes. This book offers a crisp and balanced overview of all that we need to know about these agents not only for the beginners, but also for the established clinicians having a thirst for research and detail into this drug class. Every attempt has been made to highlight the clinically relevant points that serve as a quick referral guide on the topic concerned by means of a crisp introduction and conclusion encompassing each topic being discussed in the various chapters.