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• Covers the spectrum of spinal conditions and interventions from the molecular basis to advanced surgical interventions <br/><br/>• Reviews novel pharmacologic and biologic neuroprotective and neuroregenerative strategies for spinal cord injuries <br/><br/>• Considers variety of surgical options that exist for the minority of patients that fail non-operative interventions <br/><br/>• Explores total disc replacement for both cervical and lumbar spines in order to maintain intervertebral motion and decrease the incidence of adjacent pathology <br/><br/>• Discusses most frequently used outcome measures to evaluate spinal surgery and reviews newer tools to predict outcomes and collect data.