1. Rohini Kadam is Faculty at School of Allied Health Science at at Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha. She had contributed to 3 books as an author and co-author in 6 chapters, She is post Graduate in Chemistry. 2. Prof. Anurag Luharia is presently serving as the Head, of Medical Physics & Radiological Safety at Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha. He has more than 45 scientific publications in various indices. He has written 2 chapters in Elsevier Publication book, author of 2 books, he has more than 15 years of clinical experience. He has commissioned and established various medical diagnostic, and therapeutic Radiation facilities. 3. Prof. Ashish Dilip Uke is working as an Asst. Professor at Datta Meghe Institute of Higher Education and Research, Sawangi has completed his MD in radiation oncology from Tata Memorial Hospital, Mumbai. He has contributed in various books as an author and co-author also worked on various scientific publications in various indices. 4. Prof. Monika Luharia is presently working as an Asst. Professor at Datta Meghe Institute of Higher Education and Research, Sawangi. she is post graduate in Ayurvedic Medicine from MUHS and has many scientific publications in various indices. She has contributed in various books as a author and coauthor.
<p>In the vast landscape of pharmaceutical science, medicinal chemistry serves as the cornerstone, bridging the gap between the realms of chemistry and biology. It is the art and science of designing, synthesizing, and developing pharmaceutical agents – molecules that alleviate human suffering, enhance well-being, and combat diseases.</p><p>This book, Fundamentals of Medicinal Chemistry, embarks on a comprehensive exploration of this fascinating discipline. Within these pages, readers will embark on a journey that delves into the intricacies of drug discovery and development. The preface serves as an invitation to all those curious minds who wish to grasp the fundamental concepts underlying the synthesis, structure-activity relationships, and mechanisms of action of bioactive molecules.</p><p>The journey begins with a historical overview, tracing the evolution of medicinal chemistry from ancient herbal remedies to the cutting-edge techniques of modern drug design. Understanding the historical context is essential for appreciating the strides made in contemporary medicinal chemistry. A solid foundation in organic and inorganic chemistry is vital. This book provides a clear elucidation of the chemical principles and reactions that underpin the synthesis of medicinal agents. It covers topics ranging from molecular structures and bonding to stereochemistry and reaction mechanisms, empowering readers with the essential toolkit for drug design. Medicine meets biology in this section, where readers will explore the intricacies of biological macromolecules, enzyme kinetics, and cell signalling pathways. An understanding of how drugs interact with biological targets is pivotal for rational drug design. Guided by the principles of structure-based drug design, readers will learn the art of crafting molecules with specific biological activities. The process of drug development, from target identification to clinical trials, is elucidated, shedding light on the rigorous journey from laboratory bench to bedside. The field of medicinal chemistry is dynamic, constantly evolving with advancements in technology and innovative approaches. This book highlights the latest trends, including computational drug design, fragment-based drug discovery, and the role of medicinal chemistry in personalized medicine. Real-world examples and case studies peppered throughout the book offer practical insights into the challenges and triumphs of medicinal chemists. These narratives provide context and demonstrate the application of theoretical knowledge in solving complex problems.</p><p>This book is tailored for students, professionals and researchers, in the fields of medicinal chemistry, pharmaceutical sciences, pharmacology, and biochemistry. It serves as an invaluable resource for those embarking on a career in drug discovery and development, providing a comprehensive foundation upon which to build specialized expertise. As you turn the pages of Fundamentals of Medicinal Chemistry, may you embark on a transformative intellectual journey, unlocking the mysteries of molecules and the artistry of their creators – the medicinal chemists. Armed with knowledge, curiosity, and determination, you are poised to contribute to the noble pursuit of enhancing human health through the power of medicinal chemistry.</p>
