Dr. Gayatri Gogoi MD IFCAP is currently an Associate Professor of Pathology at Assam Medical College Dibrugarh Assam. She is an International Fellow of the College of American Pathologists and an active member of the American Association for Cancer Research a top research body. Her areas of specialisation include Onco-pathology with a special interest in Breast Pathology Hematolymphoid and Endocrinal Pathology and laboratory skills in Immunohistochemistry Flow Cytometry Molecular Pathology and Cancer Genetics. She has completed specialised courses in Cancer Genomics and Precision Oncology from Harvard Medical School USA and Cancer Genetics and Hereditary Cancer Counselling and Testing from the Advanced Centre for Treatment Research and Education in Cancer (ACTREC) Navi Mumbai. She serves as the Chairperson of the North East India Genomic Consortium a professional association aimed at enhancing awareness and knowledge of genetics and genomics. Dr. Gogoi has published 49 research papers with over 300 citations to date three book chapters and over 150 popular scientific articles on health-related issues. Dr. Gogoi serves as an Editorial Board Member of the Indian Journal of Pathology and Oncology and a reviewer for several Springer Nature journals including Discover Oncology and Women's Health. She is also a project reviewer for grant agencies like the Science and Engineering Research Board and the American Association for Cancer Research (student's travel grant from India). Dr. Gogoi has over 20 years of teaching experience working with undergraduates laboratory technicians B.Sc Nursing students and guiding MD and PhD thesis. She has presented research papers at over 50 international national and regional conferences. Dr. Gogoi has conducted research as the Principal Investigator of 15 research projects (8 completed) sponsored by ICMR DBT and SERB. Dr. Gogoi has received several prestigious awards including IMA National Excellence Award in 2023 Dr. Chandra Sekhar Das Memorial Award in 2022 from Breast Cancer Hub (USA) for Outstanding Service in Cancer Care and IMA Dr. DS Munagekar National Award for Excellence in Research in 2021. Additionally she received the Director General of Police Assam Commendation Award in 2020 for innovation in Home Isolation and Quarantine Monitoring of COVID-19 and the IMA National President Appreciation Award for COVID Care and Control in 2019-2020. Dr. Gogoi was instrumental in setting up the Immunohistochemistry laboratory at Pathology AMCH which has been running successfully since 2011. Her experience in running a resource-limited setup is the foundation for writing the Handbook of Immunohistochemistry to aid budding laboratory professionals. All images published in this book are from the same manually run laboratory.
<p>Immunohistochemistry (IHC) is an indispensable ancillary technique for tissue diagnosis which enhance support to correlate and to confirm histopathology report in great variety of situations. No histopathologist will fully affirm a case of soft tissue tumours origin unless supported by immunohistochemical markers study. There are automated solutions available for high case load hospitals but it is costly and not sustainable for all laboratory set ups due to lack of affordability and lower number of histopathology sample load.</p><p><br></p><p>So economically viable and sustainable solution for small laboratory or educational institutions for academic/training purpose is a manual method of immunohistochemistry. Exclusive and detailed training and meticulous technical skill of laboratory procedure can ensure good immunohistochemistry (IHC) result which can be undertaken by technical staffs and PGTs for thesis purpose.</p><p><br></p><p>This publication briefly covers scope of IHC applications in different diagnostic and prognostic situations. It also highlights how to trouble-shoot in failure of staining inconsistent situations. It also throws light to ensure quality control in pre testing to during the testing procedure. To improve better understanding one chapter is dedicated to interpretation of staining in different cellular components with photographs and application of common antibody panels. This handbook consists of practical aspects of IHC in a step-by-step manner so that laboratory professionals have ready to refer material available with them.</p><p><br></p><p>This is a guide book for trainee laboratory technology students (DMLT, B.Sc, M.Sc) Post Graduate students of Pathology as well as Practicing Laboratory Professionals of low resource laboratory.</p>
