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• Valuable book for the novice clinicians to have a good overview on the principles underlying manual therapy. </br></br>• An ideal reference for the hands on musculoskeletal clinicians. </br></br>• Specialty of neural mobilization has been revisited, reevaluated and refined. </br></br>• An insight into what the hands on interventions aim to do for the primary musculoskeletal diagnosis. </br></br>• An overview as to how the musculoskeletal system functions as chains and links and the need for manual intervention of the complete and relevant chain.